2013 Fiscal Year Final Research Report

Construction of the prevention system of a Bisphosphonate-Related Osteonecrosis of the Jaw judging from an intraoral infection degree

Research Project

Project/Area Number	23593058
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	Periodontal dentistry
Research Institution	Okayama University
Principal Investigator	HATANAKA KAZU 岡山大学, 医歯(薬)学総合研究科, 助教 (50362992)
Co-Investigator(Kenkyū-buntansha)	TAKASHIBA Shogo 岡山大学, 医歯(薬)学総合研究科, 教授 (50226768) YAMAMOTO Todashi 岡山大学, 大学病院, 講師 (50432662) YAMASHIRO Keisuke 岡山大学, 医歯(薬)学総合研究科, 助教 (30581087)
Project Period (FY)	2011 – 2013
Keywords	感染 / 顎骨壊死
Research Abstract	The phenomenon of osteonecrosis of the jaw (ONJ) has been reported in the cancer patient who has received medication of the bisphosphonate (BP) to bone metastases. In Okayama University Hospital, the oral hygienist has been stationed in the Center for Clinical Oncology, and investigated the intraoral trouble. As a result, the Center use patients and the number of interviews by oral hygienist are increasing year by year, and were able to find six ONJ newly in three years. Those patients are followed up in the Department of Periodontics and Oral Surgery. Moreover, many of other chemotherapy patients had the symptom of stomatitis.