Improved input-function quantification in a noninvasive measurement using medical tomography

2014 Fiscal Year Final Research Report

• Project/Area Number: 23602001
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Medical Physics/Radiological Technology
• Research Institution: Hokkaido University
• Principal Investigator: KUBO Naoki 北海道大学, 安全衛生本部, 特任准教授 (80241389)
• Co-Investigator(Kenkyū-buntansha): SHIGA Tohru 北海道大学, 大学院医学研究科, 准教授 (80374495)
• Project Period (FY): 2011-04-28 – 2015-03-31
• Keywords: 入力関数 / ファントム

Outline of Final Research Achievements

Medical tomography can provide quantitative estimates of physiological or metabolic parameters. This usually requires obtaining multiple arterial blood samples during dynamic scans. As this procedure is considered a health risk for the patient and medical personnel, a measurement of arterial tracer concentration using medical tomography has been devised that can be used to obtain an input function with minimum discomfort to the patient and without drawing arterial blood. However, measured input functions in medical tomography are influenced by disturbing factors. We have developed a phantom of an arterial input-function. Correction-coefficients of the input function were obtained by means of this phantom. Thus, a measurement of arterial tracer concentration as an input function has been improved by correction-coefficients using our phantom.

Free Research Field

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