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2013 Fiscal Year Final Research Report

Conversion of CT image quality to suitable quality for images input into a computer-aided detection (CAD) system for lung cancer

Research Project

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Project/Area Number 23602005
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical Physics/Radiological Technology
Research InstitutionNiigata University

Principal Investigator

OHKUBO Masaki  新潟大学, 医歯学系, 教授 (10203738)

Co-Investigator(Kenkyū-buntansha) WADA Shinichi  新潟大学, 医歯学系, 教授 (80105519)
Research Collaborator MATSUMOTO Toru  健生クリニック
MURAO Kohei  富士通(株)
Project Period (FY) 2011 – 2013
KeywordsX線CT装置 / 変調伝達関数(MTF) / 画像再構成関数 / 点広がり関数(PSF) / 空間分解能 / 肺がん / CT検診
Research Abstract

When computer-aided detection (CAD) is applied to lung cancer screening, it is important to choose a reconstruction kernel suitable for images input into a CAD system. However, if the kernel suitable for CAD is different from the kernel that has been clinically used by a radiologist until the introduction of CAD, the change in kernel could cause difficulty. To overcome this problem, we proposed a new technique of image filtering as an alternative to the application of a different reconstruction kernel, based on the quantitative analysis of the modulation transfer function (MTF) measured in the system. It was demonstrated that the proposed method had good performance and improved the worsening in performance of CAD caused by the use of kernels unsuitable for images input into a CAD system.

  • Research Products

    (23 results)

All 2014 2013 2012 2011

All Journal Article (6 results) (of which Peer Reviewed: 6 results) Presentation (17 results)

  • [Journal Article] Observer independent nodule-detectability index for low-dose lung cancer screening CT : a pilot study2013

    • Author(s)
      Ohkubo M, Wada S, Kanai S, Ishikawa K, Marasinghe JC, Matsumoto T.
    • Journal Title

      Radiol Phys Technol

      Volume: Vol.6, No.2 Pages: 492-499

    • DOI

      10.1007/s12194-013-0225-2

    • Peer Reviewed
  • [Journal Article] Accurate determination of CT point spread function with high precision2013

    • Author(s)
      Kayugawa A, Ohkubo M, Wada S.
    • Journal Title

      J Appl Clin Med Phys

      Volume: Vol.14, No.4 Pages: 216-226

    • DOI

      10.1120/jacmp.v14i4.3905

    • Peer Reviewed
  • [Journal Article] Application of PSF-based virtual nodules to assess the performance of lung cancer CT screening CAD system2012

    • Author(s)
      Marasinghe JC, Ohkubo M, Kobayashi H, Murao K, Matsumoto T, Niizuma S, Sone S, Wada S.
    • Journal Title

      Proceedings of Asia-Oceania Congress of Medical Physics

      Volume: Vol.12 Pages: 249-252

    • Peer Reviewed
  • [Journal Article] Accuracy of lung nodule density on HRCT : analysis by PSF-based image simulation2012

    • Author(s)
      Ohno K, Ohkubo M, Marasinghe JC, Murao K, Matsumoto T, Wada S.
    • Journal Title

      J Appl Clin Med Phys

      Volume: Vol.13, No.6 Pages: 277-292

    • DOI

      10.1120/jacmp.v13i6.3868

    • Peer Reviewed
  • [Journal Article] Application of CT-PSF-based computer-simulated lung nodules for evaluating the accuracy of computer-aided volumetry2012

    • Author(s)
      Funaki A, Ohkubo M, Wada S, Murao K, Matsumoto T, Niizuma S.
    • Journal Title

      Radiol Phys Technol

      Volume: Vol.5, No.2 Pages: 166-171

    • DOI

      10.1007/s12194-012-0150-9

    • Peer Reviewed
  • [Journal Article] Image filtering as an alternative to the application of a different reconstruction kernel in CT imaging : feasibility study in lung cancer screening2011

    • Author(s)
      Ohkubo M, Wada S, Kayugawa A, Murao K, Matsumoto T.
    • Journal Title

      Medical Physics

      Volume: Vol.38, No.7 Pages: 3915-3923

    • DOI

      10.1118/1.3590363

    • Peer Reviewed
  • [Presentation] Validation of using PSF-based virtual nodules to assess the basic performances of lung cancer CT screening CAD system2014

    • Author(s)
      Marasinghe JC, Ohkubo M, Wada S, Kobayashi H, Yoshida A, Murao K, Matsumoto T, Sone S.
    • Organizer
      CARS 2014 (発表確定)
    • Place of Presentation
      福岡
    • Year and Date
      20140625-28
  • [Presentation] Influence of nodule offset in CAD performance evaluation of lung cancer CT screening2014

    • Author(s)
      Yoshida A, Ohkubo M, Kobayashi H, Marasinghe JC, Numan DMJ, Murao K, Matsumoto T, Sone S, Wada S.
    • Organizer
      第107回日本医学物理学会学術大会
    • Place of Presentation
      横浜
    • Year and Date
      20140410-13
  • [Presentation] PSF-based virtual noduleを用いた胸部CT検診CAD性能評価法の研究 : ファントム模擬結節との比較による検証2013

    • Author(s)
      小林元、大久保真樹、Marasinghe JC、村尾晃平、松本徹、曽根脩輔、和田真一
    • Organizer
      第106回日本医学物理学会学術大会
    • Place of Presentation
      大阪
    • Year and Date
      20130916-18
  • [Presentation] Evaluation of lung CT CAD performance by using PSF-based virtual nodules : a validation of the methodology2013

    • Author(s)
      Marasinghe JC, Ohkubo M, Kobayashi H, Murao K, Matsumoto T, Niizuma S, Sone S, Wada S.
    • Organizer
      ICMP 2013
    • Place of Presentation
      UK
    • Year and Date
      20130901-04
  • [Presentation] Dependency of CT CAD performance on the distance between nodule and pulmonary vessel : a study by using virtual nodules2013

    • Author(s)
      Sunitha S, Marasinghe JC, Ohkubo M, Kobayashi H, Gohdo M, Wada S.
    • Organizer
      SLJCR-2013
    • Place of Presentation
      Kandy, Sri Lanka
    • Year and Date
      20130329-31
  • [Presentation] Nodule detection by lung CT CAD : analysis by PSF-based image simulation with verification2013

    • Author(s)
      Marasinghe JC, Ohkubo M, Kobayashi H, Murao K, Matsumoto T, Niizuma S, Sone S, Wada S.
    • Organizer
      SLJCR-2013
    • Place of Presentation
      Kandy, Sri Lanka
    • Year and Date
      20130329-31
  • [Presentation] CT装置の空間分解能に基づいたvirtual noduleの生成および胸部CT検診CADの性能評価への応用 : ファントム模擬結節との比較による検証2013

    • Author(s)
      小林元、Marasinghe JC、和田真一、大久保真樹、村尾晃平、松本徹、曽根脩輔
    • Organizer
      第128回日本医学放射線学会北日本地方会、第73回日本核医学会北日本地方会
    • Place of Presentation
      新潟
    • Year and Date
      2013-06-14
  • [Presentation] Application of PSF-based virtual nodules to assess the performance of lung cancer CT screening CAD system2012

    • Author(s)
      Marasinghe JC, Ohkubo M, Kobayashi H, Murao K, Matsumoto T, Niizuma S, Sone S, Wada S.
    • Organizer
      10th SEACOMP
    • Place of Presentation
      Chiang Mai, Thailand
    • Year and Date
      20121211-14
  • [Presentation] PSF-CT画像シミュレーションと胸部CT検診画像の融合を用いたCAD性能評価の研究2012

    • Author(s)
      小林元、大久保真樹、Marasinghe JC、松本徹、曽根脩輔、和田真一
    • Organizer
      第104回日本医学物理学会学術大会
    • Place of Presentation
      つくば
    • Year and Date
      20120913-15
  • [Presentation] Performance assessment of CAD for lung cancer CT screening by applying PSF-based virtual nodules : influence on slice thickness and nodule density2012

    • Author(s)
      Marasinghe JC, Ohkubo M, Kobayashi H, Matsumoto T, Niizuma S, Sone S, Wada S.
    • Organizer
      第104回日本医学物理学会学術大会
    • Place of Presentation
      つくば
    • Year and Date
      20120913-15
  • [Presentation] 肺内結節検出CADシステムの性能評価法の研究-virtual noduleを用いた検討2012

    • Author(s)
      和田真一、大久保真樹、小林元、Chathari MM、村尾晃平、松本徹、曽根脩輔
    • Organizer
      第103回日本医学物理学会学術大会
    • Place of Presentation
      横浜
    • Year and Date
      20120412-15
  • [Presentation] 肺内結節検出用CT-CADの性能検証法の研究-virtual noduleを用いた検討2012

    • Author(s)
      和田真一、大久保真樹、舟木歩、村尾晃平、松本徹、曽根脩輔
    • Organizer
      第19回日本CT検診学会学術集会
    • Place of Presentation
      長野
    • Year and Date
      20120217-18
  • [Presentation] 肺がんCT検診用結節自動検出CADのvirtual noduleを用いた性能評価法の研究2012

    • Author(s)
      和田真一、大久保真樹、小林元、Marasinghe JC、村尾晃平、松本徹、新妻伸二、曽根脩輔
    • Organizer
      第13回新潟肺ドック研究会
    • Place of Presentation
      新潟
    • Year and Date
      2012-07-14
  • [Presentation] Accuracy evaluation of computer-aided volumetry software for lung nodule by computer-simulated nodules added onto CT images2011

    • Author(s)
      Funaki A, Wada S, Ohkubo M, Murao K, Matsumoto T, Niizuma S
    • Organizer
      第102回日本医学物理学会学術大会、(第6回日韓医学物理学術合同大会、第11回アジア・オセアニア医学物理会議)
    • Place of Presentation
      福岡
    • Year and Date
      20110929-1001
  • [Presentation] 3次元CT画像シミュレーションを用いた肺結節CT値の臨床的評価における精度解析2011

    • Author(s)
      大野健、大久保真樹、和田真一
    • Organizer
      第101回日本医学物理学会学術大会
    • Place of Presentation
      震災のためWeb開催
    • Year and Date
      20110509-20
  • [Presentation] CTシミュレーション画像とファントム画像の融合による肺内結節体積測定ツールの精度評価2011

    • Author(s)
      舟木歩、大久保真樹、和田真一、村尾晃平、松本徹
    • Organizer
      第101回日本医学物理学会学術大会
    • Place of Presentation
      震災のためWeb開催
    • Year and Date
      20110509-20
  • [Presentation] CT画像MTF高精度測定結果の応用-nodule volumetry-CAD精度検証及びCT検診撮影条件の最適化2011

    • Author(s)
      和田真一、大久保真樹、松本徹、村尾晃平、舟木歩、金井悟、粥川啓廣
    • Organizer
      第12回新潟肺ドック研究会
    • Place of Presentation
      新潟
    • Year and Date
      2011-07-23

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Published: 2015-07-16  

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