2013 Fiscal Year Final Research Report
Why methylation and demethylation occur simultaneously in cancers
| Project/Area Number |
23616001
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
epigenetics
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| Research Institution | Gunma University |
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Principal Investigator |
HATADA Izuho 群馬大学, 生体調節研究所, 教授 (50212147)
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| Co-Investigator(Kenkyū-buntansha) |
堀居 拓郎 (00361387)
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| Co-Investigator(Renkei-kenkyūsha) |
落合 孝広 (60192530)
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| Project Period (FY) |
2011 – 2013
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| Keywords | メチル化 |
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| Research Abstract |
DNA methylation is one of the modification of genes, which work as a gene switch. It inactivates tumor suppressor and cause cancer. We found specific isoform of DNMT3B DNA methyltranserase, which could cause cancer.
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