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2012 Fiscal Year Final Research Report

Research on indirect intercell-recognition in the central nervous system

Research Project

  • PDF
Project/Area Number 23650174
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Nerve anatomy/Neuropathology
Research InstitutionHamamatsu University School of Medicine

Principal Investigator

SATO Kohji  浜松医科大学, 医学部, 教授 (80235340)

Co-Investigator(Kenkyū-buntansha) MIKAWA Sumiko  浜松医科大学, 医学部, 助教 (70359743)
Project Period (FY) 2011 – 2012
Keywords神経回路網
Research Abstract

We studied whether BMP signaling pathways are involved in indirect intercell-recognition in the central nervous system. And we found that BMPs, their receptors and their antagonists were abundantly expressed in cell bodies, dendrites, axons and extracellular space. This means that BMP signaling pathways are involved in indirect intercell-recognition between projecting neurons and their receiving neurons. In future, we want to reveal which kinds of information are transmitted by this system.

  • Research Products

    (9 results)

All 2013 2012

All Journal Article (9 results) (of which Peer Reviewed: 9 results)

  • [Journal Article] Disruption of spine homeostasis causes depression2013

    • Author(s)
      Kohji. Sato
    • Journal Title

      Med Hypotheses

      Volume: S0306-9877(13) Pages: 00144-8

    • DOI

      DOI:10.1016/j.mehy.2013.03.025.

    • Peer Reviewed
  • [Journal Article] Adventitial vasa vasorum arteriosclerosis in abdominal aortic aneurysm2013

    • Author(s)
      H. Tanaka, N. Zaima, T. Sasaki, T. Hayasaka, N. Goto-Inoue, K. Onoue, K. Ikegami, Y. Morita, N. Yamamoto, Y. Mano, M. Sano, T. Saito, Kohji. Sato, H. Konno, M. Setou, N. Unno.
    • Journal Title

      PLSO ONE

      Volume: Vol.8, Nol.2

    • DOI

      DOI:10.1371/journal.pone.0057398

    • Peer Reviewed
  • [Journal Article] Matrix Metalloproteinase-2 Deficiency Impairs Aortic Atherosclerotic Calcification in ApoE-Deficient Mice2013

    • Author(s)
      T. Sasaki, K. Nakamura, K. Sasada, S. Okada, XW. Cheng, T. Suzuki, T. Murohara, Kohji. Sato, M. Kuzuya.
    • Journal Title

      Atherosclerosis

      Volume: Vol. 227, No.1 Pages: 43-50

    • DOI

      DOI:10.1016/j.atherosclerosis.2012.12.008

    • Peer Reviewed
  • [Journal Article] Placenta-derived hypo-serotonin situations in the developing forebrain cause autism.2013

    • Author(s)
      Kohji Sato
    • Journal Title

      Medical Hypotheses

      Volume: Vo l. 8 0 , No.4 Pages: 368-372

    • DOI

      DOI:10.1016/j.mehy.2013.01.002

    • Peer Reviewed
  • [Journal Article] Pre- and post-synaptic switches of GABA actions associated with Cl- homeostatic changes are induced in the spinal nucleus of the trigeminal nerve in a rat model of trigeminal neuropathic pain.2012

    • Author(s)
      B. Wei, T. Kumada, T. Furukawa, K. Inoue, M. Watanabe, Kohji Sato, A. Fukuda.
    • Journal Title

      Neursocience

      Volume: 228 Pages: 334-348

    • DOI

      DOI:10.1016/j.neuroscience.2012.10.043

    • Peer Reviewed
  • [Journal Article] Spine homeostasis as a novel therapeutic target for schizophrenia.2012

    • Author(s)
      S. Yamagishi, S. Mikawa, H. Furukawa, T. Sasaki, T. Ito, T. Ueki, Kohji Sato.
    • Journal Title

      Journal of Clinical Pharmacology & Biopharmaceutics.

      Volume: S1-001

    • Peer Reviewed
  • [Journal Article] Disruption of spine homeostasis causes dopaminergic compensatory up-regulation, resulting in schizophrenia2012

    • Author(s)
      Kohji Sato
    • Journal Title

      Medical Hypotheses

      Volume: Vol.79, No.3 Pages: 304-307

    • DOI

      DOI:10.1016/j.mehy.2012.05.015

    • Peer Reviewed
  • [Journal Article] CLP36 and RIL recruit alpha-actinin-1 to stress fibers and differentially regulate stress fiber dynamics in F2408 fibroblasts2012

    • Author(s)
      K. Miyazaki, K. Ohno, N. Tamura, T. Sasaki, Kohji Sato
    • Journal Title

      Experimental Cell Research

      Volume: Vol.318, No.14 Pages: 1716-1725

    • DOI

      DOI:10.1016/j.yexcr.2012.05.006

    • Peer Reviewed
  • [Journal Article] BMP2, BMP4, noggin, BMPRIA, BMPRIB, and BMPRII are differentially expressed in the adult rat spinal cord2012

    • Author(s)
      M. Miyagi, S. Mikawa, T. Sato, T. Hasegawa, S. Kobayashi, Y. Matsuyama, Kohji Sato
    • Journal Title

      Neuroscience

      Volume: Vol.203 Pages: 12-26

    • DOI

      DOI:10.1016/j.neuroscience.2011.12.022.

    • Peer Reviewed

URL: 

Published: 2014-09-25  

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