2013 Fiscal Year Final Research Report
Construction of original research infrastructure to investigate life phenomenon of great diversity
| Project/Area Number |
23650236
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Laboratory animal science
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| Research Institution | University of Miyazaki |
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Principal Investigator |
CHIHIRO Koshimoto 宮崎大学, フロンティア科学実験総合センター, 教授 (70295210)
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| Co-Investigator(Kenkyū-buntansha) |
EDASHIGE Keisuke 高知大学, 教育研究部, 教授 (30175228)
MORITA Tetsuo 宮崎大学, 農学部, 教授 (90301382)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 実験動物学 / バイオリソース / Apodemus speciosus / Apodemus sylvaticus / 脂質異常症（高コレステロール血症） / 生殖工学 / ゲノム科学 |
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| Research Abstract |
In order to develop a new research resource which complements the existing lab-animals such as mice and rats, breeding stock construction and property evaluation in genus Apodemus which include Japanese endemic species have been started. The research performed in Japanese endemic species (A. speciosus) and the European species (A. sylvaticus) as main targets. In the former, the world's first breeding colony has been constructed under indoor condition and fundamental technique development relating to embryo handling in vitro has been started. In the latter which can maintain indoor, it has become clearer that their hyperlipemia characteristic is corresponding to that in human but in mouse or rat. These results indicate that Apodemus could have a high potential as a unique bio-resource.
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