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2014 Fiscal Year Final Research Report

Preparation of microsphere with minute through-holes by using multi emulsion and its application

Research Project

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Project/Area Number 23656498
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Properties in chemical engineering process/Transfer operation/Unit operation
Research InstitutionSojo University

Principal Investigator

SAKOGUCHI Akihiro  崇城大学, 工学部, 教授 (30196141)

Project Period (FY) 2011-04-28 – 2015-03-31
Keywords微粒子 / 貫通型細孔 / マルチエマルション / 固定化酵素 / 糖 / マイクロリアクター / 薄膜 / 接着
Outline of Final Research Achievements

In this study, I proposed a simpler preparation method for microsphere with minute through-holes by lyophilization of O/W/O multiple emulsion. And I succeeded in immobilizing of enzyme in PEG microsphere with minute through-holes. The effects of sugar addition on enzymatic activity of the immmobilized enzyme were investigated and the optimum concentrations of sugars were found. Furthermore, it was found that immobilized enzyme in PEG microsphere with minute-holes, which adhered to the surface of microchannel by simple method, exhibited high activity.

Free Research Field

プロセス・化学工学、生体触媒工学、バイオ生産プロセス、薄膜・微粒子形成操作、分離科学工学、化工物性

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Published: 2016-06-03  

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