2012 Fiscal Year Final Research Report
Analysis of new endocrine regulatory system between posterior pituitary gland and adipose-mammary gland tissues via oxytocin receptor
| Project/Area Number |
23658219
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied animal science
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| Research Institution | Tohoku University |
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Principal Investigator |
ROH Sanggun 東北大学, 大学院・農学研究科, 准教授 (90322130)
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| Co-Investigator(Kenkyū-buntansha) |
NISHIMORI Katsuhiko 東北大学, 大学院・農学研究科, 教授 (10164609)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 代謝 / 内分泌制御 |
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| Research Abstract |
The aim of this study was to investigate 1) the expression of OXTR in adipose tissues and possible role in regulating lipid metabolism, and 2) the expression of OXTR during the differentiation of mammary epithelial cells. These results suggest 1) that up-regulation of OXTR during fat accumulation and adipocyte development may intensify the catabolic effects by oxytocin in adipose tissue to cause lipolysis, 2) OXTR expressionwas regulated by adiponectin and lactogenic hormones in bovine mammary epithelial cells.
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[Journal Article] Changes in circulating adiponectin and metabolic hormones concentrationsduring periparturient and lactation periods in Holstein dairy cows2012
Author(s)
Ohtani Y, Takahashi T, Sato K, ArdiyantiA, Song SH, Sato R, Onda K, Wada Y, ObaraY, Suzuki K, Hagino A, Roh SG and Katoh
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Journal Title
Animal Science Journal
Volume: 83(12)
Pages: 788-795
DOI
Peer Reviewed
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