2012 Fiscal Year Final Research Report
Is insulin inactivated by the binding with serum soluble insulin receptor(sIR)?
| Project/Area Number |
23659156
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
General medical chemistry
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| Research Institution | The University of Tokushima |
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Principal Investigator |
EBINA Yousuke 徳島大学, 疾患酵素学研究センター, 教授 (00112227)
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| Co-Investigator(Renkei-kenkyūsha) |
YUASA Tomoyuki 徳島大学, 疾患酵素学研究センター, 准教授 (50304556)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 生体分子医学 |
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| Research Abstract |
W e have established ultrasensitive ELISA insulin assay system.With the anti-IR antibody which does not inhibit the binding of sIR with insulin,we could measure the insulin which binds to sIR.We have succeeded to precipitate sIR-insulin complex by the monoclonal antibody 18-44 without affecting sIR-insulin complex.
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