2013 Fiscal Year Final Research Report
Development of conditionally replicating adenovirus that treats human ES/iPS-derived tumor
| Project/Area Number |
23659159
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
General medical chemistry
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| Research Institution | Kagoshima University |
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Principal Investigator |
KOSAI kenichirou 鹿児島大学, 医歯(薬)学総合研究科, 教授 (90258418)
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| Co-Investigator(Kenkyū-buntansha) |
IRIE Rie 鹿児島大学, 大学院・医歯学総合研究科, 助教 (90381178)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 再生医学 |
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| Research Abstract |
The tumor that is derived from the contaminated undifferentiated-cells is the major obstacle to the clinical application of human ES and/or iPS cell-based regenerative medicine. Here we developed a novel methodology that might conquer this obstacle to some degrees using m-CRA (conditionally replicating adenovirus with multiple tumor-specific factors), which we had initially developed for treating cancer. This methodology is not only a scientifically novel and original but also meaningful in terms of facilitating clinical development of these sorts of innovative therapy.
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Research Products
(29 results)
