2013 Fiscal Year Final Research Report
Establishment of a simulation method to evaluate a software of blood flow distribution in artificial grafts
| Project/Area Number |
23659271
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Medical sociology
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| Research Institution | Tokyo University of Technology |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
UMEZU Mitsuo 早稲田大学, 理工学術院, 教授 (90132927)
YI Qian 早稲田大学, 理工学術院, 教授 (80389147)
INOUE Nobuyuki 北里大学, 医学部, 助教 (90365122)
IRISAWA Yusuke 北里大学, 医学部, 助教 (00525537)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 医療レギュラトリーサイエンス |
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| Research Abstract |
We propose novel evaluation criteria for assessing aortic revascularization surgery from the standpoint of regulatory science using computational fluid dynamics (CFD).
In order to know the blood flow distribution in the body, we measured blood flow in the aortic arch of healthy individuals and aortic aneurysm patients by phase-contrast magnetic resonance imaging (PC-MRI). We created human blood vessel models from the MRI images of the aortic arch, and simplified branch models that represent the vessel geometry after revascularization. We used the models to examine the CFD boundary conditions corresponding to PC MRI images and established a method to analyze blood flow distribution. We also examined the computational limitations of our simplified models.
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