2012 Fiscal Year Final Research Report
Challenging research for elucidating the role of oral bacteria in the pathogenesis of IBD
| Project/Area Number |
23659402
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Gastroenterology
|
|---|
| Research Institution | Yokohama City University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
WADA Koichiro 大阪大学, 歯学研究科, 准教授 (90263467)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Keywords | 炎症性腸疾患 / 齲蝕菌 |
|---|
| Research Abstract |
The pathogenesis of Inflammatory Bowel Disease (IBD) is still unknown. Caries bacteria, Streptococcus mutans (S. mutans) is known to cause the systemic disease such as endocarditis or sepsis. We have recently found that special types of S. mutans had tendency cause the systemic disease. In this research, we elucidate the role of S. mutans in the pathogenesis of the IBD using animal model and patients samples, and evaluate the risk for the developing the IBD.
|
Research Products
(14 results)
