2012 Fiscal Year Final Research Report
Killer T cell inducing peptide vaccine against malaria infection
| Project/Area Number |
23659504
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Infectious disease medicine
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| Research Institution | Hokkaido University |
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Principal Investigator |
KAJINO Kiichi 北海道大学, 人獣共通感染症リサーチセン ター, 准教授 (80322147)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 感染症防御学 |
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| Research Abstract |
Six potent Cytotoxic T cell inducing 9mer peptide that derived from Plasmodium falciparum were indentified. Out of 6, immunization of HLA-A24 transgenic mice with 3 peptides partially protected mice from lethal malaria infection. This results suggest that CTL inducing malaria vaccine is promising new vaccine.
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