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2012 Fiscal Year Final Research Report

Induction of differentiation to musculoskeletal tissue with autologous blood-derived scaffold and application to regenerative medicine

Research Project

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Project/Area Number 23659722
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Orthopaedic surgery
Research InstitutionOsaka University

Principal Investigator

KITA Keisuke  大阪大学, 医学系研究科, 特任助教(常勤) (30588869)

Co-Investigator(Kenkyū-buntansha) NAKATA Ken  大阪大学, 医学系研究科, 講師 (00283747)
MAE Tatsuo  大阪大学, 医学系研究科, 助教 (10569734)
HIGUCHI Chikahisa  大阪大学, 医学系研究科, 助教 (40432421)
NAKAMURA Norimasa  大阪大学, 臨床医工学融合教育センター, 招聘教授 (50273719)
MYOI Akira  大阪大学, 医学部附属病院, 准教授 (10263261)
YOSHIKAWA Hideki  大阪大学, 医学系研究科, 教授 (60191558)
Project Period (FY) 2011 – 2012
Keywords四肢機能再建学
Research Abstract

In recent years, usefulness of the technique using artificial materials and animal-derived materials has been reported in the treatment of meniscus which is one of the tissue forming the synovial joint. However, the problems to be overcome, such as infection control and immune response, are still present. The most effective way to solve these problems is to use autologous materials only. Fibrin clot is a tissue with a network structure and is easily created from venous blood. Fibrin clot is highly safe because it is autologous. In this study, we examined the regenerative therapy of meniscus using the fibrin clot.

  • Research Products

    (4 results)

All 2013 2012

All Presentation (4 results)

  • [Presentation] 自己由来滑膜細胞とフィブリンクロットを用いた一期的半月板再生治療の試み2013

    • Author(s)
      北圭介、中田研、前達雄、米谷泰一、中村憲正、松尾知彦、橘優太、金銅真世、太田啓介、吉川秀樹
    • Organizer
      第5回日本関節鏡・膝・スポーツ整形外科学会
    • Place of Presentation
      第5回日本関節鏡・膝・スポーツ整形外科学会
    • Year and Date
      2013-06-20
  • [Presentation] 膝関節半月板再生のためのコラーゲン補填材料 ミニブタを用いた feasibility study2013

    • Author(s)
      北圭介、前達雄、米谷泰一、松尾知彦、橘優太、金銅真世、吉川秀樹、中田研
    • Organizer
      第12回日本再生医療学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-22
  • [Presentation] 自家細胞と自家静脈血フィブリンによる一期的cell delivery system -半月細胞を用いた検討-2012

    • Author(s)
      北圭介、中田研、前達雄、中村憲正、松尾知彦、金銅真世、太田啓介、吉川秀樹
    • Organizer
      第27回日本整形外科学会基礎学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-10-26
  • [Presentation] 関節内骨軟骨欠損に対する軟骨下骨修復材料の検討2012

    • Author(s)
      北圭介、前達雄、松尾知彦、下村和範、中村憲正、吉川秀樹、中田研
    • Organizer
      第4回日本関節鏡・膝・スポーツ整形外科学会
    • Place of Presentation
      沖縄
    • Year and Date
      2012-07-20

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Published: 2014-09-25  

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