2012 Fiscal Year Final Research Report
Clinical features of cervical cancer and type of human papillomavirus; especially the features and HPV18
| Project/Area Number |
23659770
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
SATHO Toyomi 筑波大学, 医学医療系, 准教授 (80344886)
MATSUMOTO Kouji 筑波大学, 医学医療系, 准教授 (30302714)
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| Project Period (FY) |
2011 – 2012
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| Keywords | HPV / 子宮頸がん / 組織型 / HPV型 |
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| Research Abstract |
Clinical features were compared among the following 3 groups: Group 18 (48 patients positive for HPV 18), Group 16 (104 patients positive for HPV 16) and Group 0 (47 patients positive for the other HPV types). Occurrence of adenocarcinoma was higher in Group 18 (47.9%) than in Group 16 (27.9%) (P =0.004). The mean age of the patients at onset was different among the 3 groups (Group18, 47.4 years; Group 16, 47.7 years; Group 0, 55.0 years (P < 0.01). In patients with stage II or more, Group 18 had a poorer prognosis than Groups 16 and Group O (P =0.03).
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Research Products
(35 results)
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[Journal Article] HLA Class II DRB1*1302 1 allele protects against progression to cervical intraepithelial neoplasia grade 3: A multicenter, prospective, cohort study2012
Author(s)
Matsumoto K, Maeda H, Oki A, Takatsuka N, Yasugi T, Furuta R, Hirata R, Mitsuhashi A, Fujii T, Hirai Y, Iwasaka T, Yaegashi N, Watanabe Y, Nagai Y, Kitagawa T, Yoshikawa H
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Journal Title
Int J Gynecol Cancer
Volume: 22(3)
Pages: 471-478
DOI
Peer Reviewed
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[Journal Article] Do neutralizing antibody responses generated by human papillomavirus infections favor a better outcome of low-grade cervical lesions?2012
Author(s)
Ochi H, Matsumoto K, Kondo K, Oki A, Furuta R, Hirai Y, Yasugi T, Takatsuka N, Maeda H, Mitsuhashi A, Fujii T, Kawana K, Iwasaka T, Yaegashi N, Watanabe Y, Nagai Y, Kitagawa T, Kanda T, Yoshikawa H
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Journal Title
J Med Virol
Volume: 84(7)
Pages: 1128-1134
DOI
Peer Reviewed
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[Journal Article] Guidelines for office gynecology in Japan: Japan Society of Obstetrics and Gynecology and Japan Association of Obstetricians and Gynecologists 2011 edition2012
Author(s)
Takeda T, Wong TF, Adachi T, Ito K, Uehara S, Kanaoka Y, Kamada M, Kitagawa H, Koseki S, Gomibuchi H, Saito J, Shirasu K, Sueoka K, Sugimoto M, Suzuki M, Sumi T, Takeda S, Tasaka K, Noguchi Y, Fujii S, Fujii T, Fujiwara M, Maeda T, Matsumoto K, Momoeda M
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Journal Title
J Obstet Gynaecol Res
Volume: 38(4)
Pages: 615-631
DOI
Peer Reviewed
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[Journal Article] Subsequent risks for cervical precancer and cancer in women with low-grade squamous intraepithelial lesions unconfirmed by colposcopy-directed biopsy: results from a multicenter, prospective, cohort study2012
Author(s)
Matsumoto K, Hirai Y, Furuta R, Takatsuka N, Oki A, Yasugi T, Maeda H, Mitsuhashi A, Fujii T, Kawana K, Iwasaka T, Yaegashi N, Watanabe Y, Nagai Y, Kitagawa T, Yoshikawa H
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Journal Title
Int J Clin Oncol
Volume: 17(3)
Pages: 233-239
DOI
Peer Reviewed
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[Journal Article] Association between carotenoids and outcome of cervical intraepithelial neoplasia: a prospective cohort study
Author(s)
Fujii T, Takatsuka N, Nagata C, Matsumoto K, Oki A, Furuta R, Maeda H, Yasugi T, Kawana K, Mitsuhashi A, Hirai Y, Iwasaka T, Yaegashi N, Watanabe Y, Nagai Y, Kitagawa T, and Yoshikawa H
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Journal Title
Peer Reviewed
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[Journal Article] Incidence of venousthromboembolism before treatment in cervical cancer and the impact of management on venous thromboembolism after commencement of treatment
Author(s)
Satoh T, Matsumoto K, Tanaka YO, Akiyama A, Nakao S, Sakurai M, Ochi H, Onuki M, Minaguchi T, Sakurai H, Yoshikawa H.
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Journal Title
DOI
Peer Reviewed
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[Presentation] Does paclitaxel plus carboplatin (TC) substitute for paclitaxel plus cisplatin (TP) in cervical cancer without prior platinum treatment? (subset analysis of Japan Clinical Oncology Group trial (JCOG 0505).2012
Author(s)
Tanabe H,Kitagawa R,Shibata T,Saito M,Okamoto A,Takakura S,Sasaki H,Ochiai K,Yoshikawa H,Kamura T
Organizer
The 37th ESMO
Place of Presentation
Vienna,Austria
Year and Date
20120928-1002
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