2013 Fiscal Year Final Research Report
Development of animal model with esophageal atresia
| Project/Area Number |
23659824
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Pediatric surgery
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| Research Institution | Jichi Medical University |
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Principal Investigator |
ONO Shigeru 自治医科大学, 医学部, 准教授 (00315962)
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| Co-Investigator(Kenkyū-buntansha) |
SASAKI Yasunari 京都府立医科大学, 医学研究科, その他 (30405253)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 先天性食道閉鎖症 / 動物モデル |
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| Research Abstract |
The aim of this study is the development of animal model with esophageal atresia to develop a new treatment procedure including surgical technique. We tried to develop rabbit model with esophageal atresia using oral administration of Retinoic acid. Variety of doses of all-trans Retinoic acid were administrated, however no anomaly including esophageal atresia were observed excepting some melting fetus.
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