2012 Fiscal Year Final Research Report
Identification of allergens for metal allergy by hydrodynamic voltammetry.
Project/Area Number |
23659927
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Dental engineering/Regenerative dentistry
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Research Institution | Matsumoto Dental University |
Principal Investigator |
|
Research Collaborator |
MIROSLAV Marek ジョージア工科大学, 材料工学, 教授
|
Project Period (FY) |
2011 – 2012
|
Keywords | 金属アレルギー / 回転リングディスク電極法 / アレルゲン / 対流ボルタンメトリー / タンパク質 / アミノ酸 / 金属イオン / 酸化-還元曲線 |
Research Abstract |
It is said that the allergen for metal allergy is produced by the protein in human body and the released metal ions. However the kinds of protein in human body are too much. An amino acid is the smallest structured unit of protein. Therefore as first step, the reaction was investigated between the amino acid and metal.The aim of this study was to identify potential allergens for metal allergy. The electrochemical interaction between pure metals and amino acid was examined by hydrodynamic voltammetry.
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Research Products
(1 results)