2013 Fiscal Year Final Research Report
Biochemical marker for prediction of exercise training-induced improvement of arterial stiffness
| Project/Area Number |
23680071
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied health science
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| Research Institution | Ritsumeikan University |
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Principal Investigator |
MOTOYUKI Iemitsu 立命館大学, スポーツ健康科学部, 准教授 (90375460)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Keywords | 動脈硬化 / 有酸素性運動 / バイオマーカー |
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| Research Abstract |
This study aimed to clarify the effects of regular aerobic exercise on apelin concentrations in middle-aged and older adults. Thirty-four healthy middle-aged and older subjects were randomly divided into two groups: exercise intervention and sedentary controls. Subjects in the training group completed 8-week of aerobic exercise training (60-70% peak oxygen uptake [VO2peak] for 45 min, 3 days/week). In the training group, VO2peak was significantly increased, and carotid beta-stiffness was significantly decreased, after the intervention. Moreover, plasma apelin and NOx levels were significantly increased in the training group after the intervention. Additionally, there was a correlation between the training effects of plasma apelin levels and carotid beta-stiffness (r = -0.508, P = 0.032). These results suggest that the increased in plasma apelin levels may be associated with exercise training-induced alternation of arterial stiffness in middle-aged and older adults.
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[Journal Article]2014
Author(s)
Matsuo T, Saotome K, Seino S, Shimojo N, Matsushita A, Iemitsu M, Ohshima H, Tanaka K, Mukai C. Effects of a low-volume aerobic-type interval exercise on VO2max and cardiac mass. Med Sci Sports Exerc
Volume
46(10.1249/MSS.0b013e3182a38da8)
Pages
42-50
Peer Reviewed
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[Journal Article] Habitual rowing exercise is associated with high physical fitness without affecting arterial stiffness in older men2012
Author(s)
Kawano H, Iemitsu M, Gando Y, Ishijima T, Asaka M, Aoyama T, Ando T, Tokizawa K, Miyachi M, Sakamoto S, Higuchi M
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Journal Title
J Sports Sci
Volume: 30(10.1080/02640414.2011.635311)
Pages: 241-246
Peer Reviewed
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[Journal Article] Associations among objectively measured physical activity, fasting plasma homocysteine concentration, and MTHFR C677T genotype2011
Author(s)
Murakami H, Iemitsu M, Sanada K, Gando Y, Ohmori Y, Kawakami R, Sasaki S, Tabata I, Miyachi M
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Journal Title
Eur J Appl Physiol
Volume: 111(10.1007/s00421-011-1926-z)
Pages: 2997-3005
Peer Reviewed
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[Presentation] Ghrelin Leu72Met polymorphism affects a relationship between HDL cholesterol and cardiorespiratory fitness level in middle and older adults2013
Author(s)
Kono S, Iemitsu M, Murakami H, Fujie S, Sanada K, Kawano H, Gando Y, Kawakami R, Tanaka N, Miyachi M
Organizer
18th Annual Meeting of European College of Sport Science Annual Congress, National Institute of Physical Education of Catalonia
Place of Presentation
Barcelona, Spain
Year and Date
2013-06-27
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[Presentation] Myocardial Mass Increases with both Sprint- and Aerobic-type Interval Exercise but not with a Traditional, Continuous Aerobic Exercise in Sedentary Adults : An 8-week Randomized Intervention Study2012
Author(s)
Matsuo T, Saotome K, Seino S, Shimojo N, Matsushita A, Iemitsu M, Ohshima H, Tanaka K, Mukai C
Organizer
American Heart Association 2012 Scientific Sessions
Place of Presentation
Los Angeles Convention Center, Los Angeles, USA
Year and Date
2012-11-06
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