2013 Fiscal Year Final Research Report
Synthesis of N-Containing Heterocycles Based on the Invention of Azametallacycles
| Project/Area Number |
23685019
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (A)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Synthetic chemistry
|
|---|
| Research Institution | Kyoto University |
|---|
Principal Investigator |
MIURA Tomoya 京都大学, 工学(系)研究科(研究院), 准教授 (10378804)
|
|---|
| Project Period (FY) |
2011-04-01 – 2014-03-31
|
| Keywords | 選択的合成 / 環境調和型反応 / 含窒素へテロ環化合物 / ロジウム / 触媒反応 |
|---|
| Research Abstract |
1-Sulfonyl-1,2,3-triazoles, which can be easily prepared from terminal alkynes by the copper-catalyzed 1,3-dipolar cycloaddition reaction with N-sulfonyl azides, have recently received much attention as precursors of carbenoid species. Their ring-chain tautomerization forms alpha-diazo imines, which react with transition-metal complexes to generate the corresponding alpha-imino metal carbenes. We have developed various types of new transformations starting from terminal alkynes via alpha-imino metal carbenes. These methods provide a highly step-economical route to complex molecules (N-containing heterocycles) in one pot.
|
-
-
-
-
-
[Journal Article] Stereoselective Synthesis of 2,3-Dihydropyrroles from Terminal Alkynes, Azides, and α,β-Unsaturated Aldehydes via N-Sulfonyl-1,2,3-triazoles2013
Author(s)
Tomoya Miura, Takamasa Tanaka, Kentaro Hiraga, Scott G. Stewart, Masahiro Murakami
-
Journal Title
J . Am. Chem. Soc
Volume: 135
Pages: 13652-13655
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] Stereoselective Synthesis of 2,3-Dihydropyrroles from Terminal Alkynes, Azides, and α,β-Unsaturated Aldehydes via N-Sulfonyl-1,2,3-triazoles2013
Author(s)
Tomoya Miura,Takamasa Tanaka, Kentaro Hiraga, Scott G.Stewart, Masahiro Murakami
Organizer
The Eighth International Symposium on Integrated Synthesis (ISIS-8)
Place of Presentation
奈良 (ポスター発表)
Year and Date
20131129-1201
-
-
-
-
-
-
-
-
