Development of a fabrication method for a functionally collaborating cellular device utilizing stem cells

2014 Fiscal Year Final Research Report

• Project/Area Number: 23686119
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Single-year Grants
• Research Field: Biofunction/Bioprocess
• Research Institution: Hiroshima University (2012-2013); Tokyo University of Agriculture and Technology (2011)
• Principal Investigator: FUNABASHI Hisakage 広島大学, サステナブル・ディベロップメント実践研究センター, 特任講師 (60552429)
• Project Period (FY): 2011-04-01 – 2015-03-31
• Keywords: 細胞デバイス / 遺伝子発現制御 / 分化誘導 / 遺伝子発現解析 / イメージング解析 / インスリン / バイオセンサー

Outline of Final Research Achievements

In this research, we have developed “a basic technique for inducing cellular differentiation by the down regulation of the activity of a target transcription factor based on the evaluation of gene expression status in a target cell” and “a basic technique for online insulin monitoring which can be applied to the evaluation of cellular functional collaboration”. These two basic techniques are expected to be applied to a fabrication method for “a cellular device in which various types of cells derived from stems cells functionally collaborate”.

Free Research Field

生物工学