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2012 Fiscal Year Final Research Report

Development of a minimally-invasive ECoGmeasurement employing smart metal and MEMS technologies

Research Project

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Project/Area Number 23700493
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Fusional brain recording science
Research InstitutionShizuoka University

Principal Investigator

YAMAKAWA Toshitaka  静岡大学, 工学部, 助教 (60510419)

Project Period (FY) 2011 – 2012
Keywords脳活動記録(レコーディング)
Research Abstract

An electrode array which can be implanted with a minimally-invasive procedure and measures ECoG of a wider cortical region than the cranial window with a high spatial resolution have been developed employing MEMS fabrication technology. The safety and capability of the electrodes were confirmed in the phantom experiments which models subdural chronic implantation, and were evaluated with animal tests using monkeys.

  • Research Products

    (19 results)

All 2013 2012 2011 Other

All Journal Article (3 results) Presentation (15 results) Remarks (1 results)

  • [Journal Article] Neuroprotective Effects of Focal Brain Cooling on Photochemically-Induced Cerebral Infarction in Rats: Analysis from a Neurophysiological Perspective2013

    • Author(s)
      Yeting He, Masami Fujii, Takao Inoue, Sadahiro Nomura, Yuichi Maruta, Fumiaki Oka, Satoshi Shirao, Yuji Owada, Hiroyuki Kida, Ichiro Kunitsugu, Toshitaka Yamakawa, Tatsuji Tokiwa, Takeshi Yamakawa, Michiyasu Suzuki
    • Journal Title

      Brain Research

      Volume: Vol. 1497 Pages: 53-60

    • DOI

      DOI:10.1016/j.brainres.2012.11.041

  • [Journal Article] Cooling of the Epileptic Focus Suppresses Seizures with Minimal Influence on Neurologic Functions2012

    • Author(s)
      Masami Fujii, Takao Inoue, Sadahiro Nomura, Yuichi Maruta, Yeting He, Hiroyasu Koizumi, Satoshi Shirao, Yuji Owada, Ichiro Kunitsugu, Toshitaka Yamakawa, Tatsuji Tokiwa, Satoshi Ishizuka, Takeshi Yamakawa and Michiyasu Suzuki
    • Journal Title

      Epilepsia

      Volume: Vol. 53, No. 3

    • DOI

      DOI:10.1111/j.1528-1167.2011.03388.x

  • [Journal Article] Subdural Electrocorticogram Measurement with a Minimally-Invasive Procedure using an SMA-Manipulated Microelectrode Array2011

    • Author(s)
      Toshitaka Yamakawa, Takeshi Yamakawa, S. Aou, S. Ishizuka, M. Suzuki, M. Fujii, T. Aoki
    • Journal Title

      Advanced Materials Research

      Volume: Vol.222 Pages: 313-317

    • DOI

      DOI:10.4028/www.scientific.net/AMR.222.313

  • [Presentation] A Minimally Invasive Brain-Machine Interface Employing Flexible Electronics2012

    • Author(s)
      Toshitaka Yamakawa, Toru Aoki, Takao Inoue, Masami Fujii, Michiyasu Suzuki, Takeshi Yamakawa
    • Organizer
      The 14th Takayanagi Kenjiro Memorial Symposium - Toward Advanced Imagince Science Creation
    • Place of Presentation
      浜松市
    • Year and Date
      20121100
  • [Presentation] Flexible Electronics for Diagnostics and Treatment of Intractable Epilepsy2012

    • Author(s)
      Toshitaka Yamakawa, Toru Aoki, Takao Inoue, Masami Fujii, Michiyasu Suzuki, Takeshi Yamakawa
    • Organizer
      13th International Young Scientists Conference Optics and High Technology Material Science - SPO 2012
    • Place of Presentation
      Kyiv(ウクライナ)
    • Year and Date
      20121000
  • [Presentation] Measurement Sensitivity of Deep Artery on Transabdominal Fetal Pulse Oximetry2012

    • Author(s)
      Tetsuya Iwano, Norbert Stuban, Toshitaka Yamakawa, Masatsugu Niwayama
    • Organizer
      34th Annual International IEEE EMBS Conference
    • Place of Presentation
      San Diego(米国)
    • Year and Date
      20120800
  • [Presentation] Theoretical and Experimental Study for Determination of Characteristics of Bone Tissue Using Diffuse Reflectance2012

    • Author(s)
      Daisuke Wakabayashi, Kazuki Wakamori, Toshitaka Yamakawa, Masatsugu Niwayama
    • Organizer
      34th Annual International IEEE EMBS Conference
    • Place of Presentation
      San Diego(米国)
    • Year and Date
      20120800
  • [Presentation] Design and Electrochemical Characterization of Polyimide Based Subdural Grid Electrodes for Minimally-Invasive Implantation2012

    • Author(s)
      Manato Kimura, Toru Aoki, Masatsugu Niwayama, Toshitaka Yamakawa
    • Organizer
      34th Annual International IEEE EMBS Conference
    • Place of Presentation
      San Diego(米国)
    • Year and Date
      20120800
  • [Presentation] Development of a Focal Brain Cooling Device for the Treatment of Intractable Epilepsy2012

    • Author(s)
      Toshitaka Yamakawa, Takeshi Yamakawa, Takao Inoue, Tatsuji Tokiwa, Shuji Aou, Toru Aoki, Yuichi Maruta, Masami Fujii, Michiyasu Suzuki
    • Organizer
      International Conference on Advanced Materials
    • Place of Presentation
      Colombo(スリランカ)
    • Year and Date
      20120700
  • [Presentation] Cool the Brain: A novel strategy to control the abnormal brain activity2011

    • Author(s)
      Toshitaka Yamakawa, Takeshi Yamakawa, Takao Inoue, Tatsuji Tokiwa, Shuji Aou, Toru Aoki, Yuichi Maruta, Masami Fujii, Michiyasu Suzuki
    • Organizer
      12th International Young Scientists Conference Optics and High Technology Material Science - SPO 2011
    • Place of Presentation
      Kyiv(ウクライナ)
    • Year and Date
      20111000
  • [Presentation] Minimally-Invasive Epileptogenic Focus Detection Using the Subdural Electrodes Manipulated by the Shape-Memory-Alloy Thin Wire2011

    • Author(s)
      Toshitaka Yamakawa, Takeshi Yamakawa, Takao Inoue, Shuji Aou, Tatsuji Tokiwa, Masami Fujii, Michiyasu Suzuki
    • Organizer
      2011 International Conference on Systems, Man, Cybernetics
    • Place of Presentation
      Anchorage(米国)
    • Year and Date
      20111000
  • [Presentation] Development of a focal cerebral cooling system for the treatment of intractable epilepsy: An experimental study in cats and non-human primates2011

    • Author(s)
      Takao Inoue, Masami Fujii, Yeting He, Yuichi Maruta, Hiroyuki Kida, Sadahiro Nomura, Michiyasu Suzuki, Toshitaka Yamakawa, Tatsuji Tokiwa, Takeshi Yamakawa, Kenichi Hirano, Masanori Niiyama, Hiromi Yamazaki
    • Organizer
      2011 International Conference on Systems, Man, Cybernetics
    • Place of Presentation
      Anchorage(米国)
    • Year and Date
      20111000
  • [Presentation] Alterative treatment of intractable epilepsy with focal brain cooling -A review of our past studies2011

    • Author(s)
      Masami Fujii, Takao Inoue, Yeting He, Yuichi Maruta, Hirochika Imoto, Hiroyasu Koizumi, Sadahiro Nomura, Tatsuji Tokiwa, Satoshi Ishizuka, Takeshi Yamakawa, Toshitaka Yamakawa
    • Organizer
      2011 International Conference on Systems, Man, Cybernetics
    • Place of Presentation
      Anchorage(米国)
    • Year and Date
      20111000
  • [Presentation] Minimally-invasive ECoG recording using the novel subdural electrodes manipulated by a shape memory alloy guidewire2011

    • Author(s)
      Toshitaka Yamakawa, Takeshi Yamakawa, Takao Inoue, Shuji Aou, Satoru Ishizuka, Masami Fujii, Michiyasu Suzuki
    • Organizer
      29th International Epilepsy Congress
    • Place of Presentation
      Rome(イタリア)
    • Year and Date
      20110800
  • [Presentation] Alterative treatment of intractable epilepsy with focal brain cooling2011

    • Author(s)
      Masami Fujii, Takao Inoue, Y. He, H. Imoto, N. Tanaka, T. Oku, Yuichi Maruta, H. Koizumi, S. Nomura, Y. Owada, T. Saito, Toshitaka Yamakawa, T. Tokiwa, Takeshi Yamakawa, Michiyasu Suzuki
    • Organizer
      29th International Epilepsy Congress
    • Place of Presentation
      Rome(イタリア)
    • Year and Date
      20110800
  • [Presentation] Energy Discriminated X-ray CT using High Count Rate Photon2011

    • Author(s)
      Toru Aoki, Akifumi Koike, Takaharu Okunoyama, Hisashi Morii, Shailendra Singh, Manato Kimura, Toshitaka Yamakawa, Hidenori Mimura
    • Place of Presentation
      San Diego(米国)
    • Year and Date
      20110800
  • [Presentation] Carrier Transportation Properties in M-p-n and Schottky CdTe Diode2011

    • Author(s)
      Manato Kimura, Akifumi Koike, Takaharu Okunoyama, Hisashi Morii, Shailendra Singh, Toshitaka Yamakawa, Hidenori Mimura, Toru Aoki
    • Organizer
      2011 SPIE Optics + Photonics
    • Place of Presentation
      San Diego(米国)
    • Year and Date
      20110800
  • [Presentation] A Low-Cost Long-Life R-R Interval Telemeter with Automatic Gain Control for Various ECG Amplitudes2011

    • Author(s)
      Toshitaka Yamakawa, Genki Matsumoto, Toru Aoki
    • Organizer
      Inter-Academia 2011
    • Place of Presentation
      Sucevita(ルーマニア)
    • Year and Date
      20110800
  • [Remarks]

    • URL

      http://www.ipc.shizuoka.ac.jp/ttyamak/

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Published: 2014-09-25  

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