2012 Fiscal Year Final Research Report
Automated construction of microtubule networks using MEMS tweezersfor transporting extremely smallouantm
| Project/Area Number |
23710108
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Nanostructural science
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| Research Institution | The University of Tokyo |
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Principal Investigator |
TARHAN Mehmetc 東京大学, 生産技術研究所, 特任研究員 (50582839)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 分子移動システム / 直接分子操作 / イメージプロセス / MEMS ピンセット / 微小管 |
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| Research Abstract |
Intracellular transport is based on motor pr,oteei.ng. kinesin,motion along rail structures, e.g. microtubule.s This works aims at buildinignavnitroreconstruction ofthe intracellular transport with singlmeicrotubules filaments to usefor the handling of extremely small amount of analytes in a microfluidic chip. To achieve this goal, MEMS tweezers were used to capture amicsriontgulbeules filament and thenrelocated to a p-dresignated area. Repeating the capturing and relocation sateps, microtubule network could be assembled for kinesin motion to use beads for carryingextremely small amounts of analytes in a chemical detection system.
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