2013 Fiscal Year Final Research Report
Application of biogenic stealthy gold/magnetic composite nanoparticle to MRI contrast agent
| Project/Area Number |
23710133
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | Osaka Prefecture University |
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Principal Investigator |
KINOSHITA Takuya 大阪府立大学, 工学(系)研究科(研究院), 助教 (90453141)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 磁性ナノ粒子 / MRI造影剤 / PEG / 噴霧熱分解法 / ハイパーサーミア |
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| Research Abstract |
Magnetic composite nanoparticles with in vivo dispersibility, stealthy and capacity to bind a targeting biomolecule have been synthesized. Magnetic iron oxide nanoparticles synthesized by co-precipitation method were utilized as a core of composite particle. Polyethylene glycol or gold was bound on the surface of iron oxide. Magnetic La-Sr-Mn oxide fine particles were synthesized for cancer treatment. These particles generated heat in the AC magnetic field, and particle temperature increased quickly with time, attaining constant values.
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