2013 Fiscal Year Final Research Report
Applications of computational homology to medical imaging analysis
| Project/Area Number |
23740084
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
General mathematics (including Probability theory/Statistical mathematics)
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| Research Institution | Asahikawa Medical College (2012-2013)
Chitose Institute of Science and Technology (2011) |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
KAMIYA Takeshi 琉球大学, 医学部付属病院, 医員 (70640647)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 計算トポロジー / 数値解析 / 骨梁構造 |
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| Research Abstract |
We demonstrated the applications of computational homology theory to medical imaging analysis implementing the mathematical software to evaluate the connectivity of trabecular bone 3D structure. By investigating the high resolution micro CT data of tendon graft model in rabbits using our software, we characterized the prevention of bone-tunnel enlargement through the administration of therapeutic drugs. The drug and control groups are significantly separated with respect to the 3D Betti numbers computed from the data of trabecular bone 3D structures.
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