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2012 Fiscal Year Final Research Report

Development of highly sensitive bio-immunoassay sensor using Brownian relaxation of the magnetic nanoparticle

Research Project

  • PDF
Project/Area Number 23760369
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Measurement engineering
Research InstitutionKyushu University

Principal Investigator

YOSHIDA Takashi  九州大学, システム情報科学研究院, 助教 (30380588)

Project Period (FY) 2011 – 2012
Keywords計測システム / バイオセンサ
Research Abstract

Immunoassay is a test that uses the binding of antibodies to antigens to identify and measure certain disease related protein or pathogenic bacteria. In this study, we developed a rapid and highly sensitive bio-immunoassay sensor system using Brownian relaxation of the magnetic nanoparticles. We could detect 10-6biotins and achieved a detection sensitivity of 20 amol/ml.

  • Research Products

    (5 results)

All 2013 2012 2011

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (2 results)

  • [Journal Article] Evaluation of Harmonic Signals for the Detection of Magnetic Nanoparticles2012

    • Author(s)
      T. Yoshida, N.B. Othman, T. Tsubaki, J. Takayama, K. Enpuku
    • Journal Title

      IEEE Transactions on Magnetics

      Volume: Vol. 48 Pages: 3788-3791

    • DOI

      DOI:10.1109/TMAG.2012.2198198

    • Peer Reviewed
  • [Journal Article] Magnetic fluid dynamics in a rotating magnetic field2012

    • Author(s)
      T. Yoshida, K. Enpuku, J. Dieckhoff, M. Schilling, and F. Ludwig
    • Journal Title

      Journal of Applied Physics

      Volume: Vol.111 Pages: 053901-1-10

    • DOI

      DOI:10.1063/1.3688254

    • Peer Reviewed
  • [Journal Article] Detection of Magnetic Nanoparticles Using the Second-Harmonic Signal2011

    • Author(s)
      T. Yoshida, K. Ogawa, T. Tsubaki, N. B. Othman, and K. Enpuku
    • Journal Title

      IEEE Transactions on Magnetics

      Volume: Vol. 47 Pages: 2863-2866

    • DOI

      DOI:10.1109/TMAG.2011.2157805

    • Peer Reviewed
  • [Presentation] ブラウン緩和を用いた液相でのバイオ免疫検査法の開発2013

    • Author(s)
      平田 智一、吉田 敬、圓福 敬二
    • Organizer
      電気学会マグネティックス研究
    • Place of Presentation
      東京
    • Year and Date
      2013-02-28
  • [Presentation] Nonlinear Behavior of Magnetic Fluid in Brownian Relaxation: Numerical Simulation and Derivation ofEmpirical Model2012

    • Author(s)
      T. Yoshida, K. Enpuku
    • Organizer
      International Workshop on Magnetic Particle Imaging
    • Place of Presentation
      Lubeck, Germany
    • Year and Date
      2012-03-15

URL: 

Published: 2014-09-25  

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