2012 Fiscal Year Final Research Report
Preparation of bioresorbable bone-repairing materials which promote bone regeneration
| Project/Area Number |
23760630
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Inorganic materials/Physical properties
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 機能性セラミックス |
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| Research Abstract |
We aimed the preparation of bioresorbable bone-repairing materials which promote bone regeneration. We prepared silicate-containing tricalcium phosphate (TCP) and revealed that the sintered silicate-containing TCP showed higher apatite-forming ability in a simulated body fluid than the silicate-free TCP. When the compact of silicate-containingTCP powder was hydrothermally treated, the Ca-deficient HA ceramic composed of rod-shaped particles was obtained. On the other hand, we revealed that the dissolution rate of the Ca-deficient in the acidic buffer solution increased with the Ca-deficiency degree. We established the synthesis process and evaluated the basic materials.
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