2012 Fiscal Year Final Research Report
Function and application of a new glycated peptide withanti-biofilm effect
| Project/Area Number |
23780137
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Food science
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| Research Institution | Kyushu University |
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Principal Investigator |
NOMA Seiji 九州大学, 大学院・農学研究院, 助教 (40392071)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 糖付加 / ペプチド / バイオフィルム |
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| Research Abstract |
LK(Glc)G has shown to have an inhibitory effect on biofilm formation in Staphylococcus aureuscells. LK(Glc)G decreased cell proliferation and appeared to alter the behavior of cell adhesion. The inhibitory effect was disappeared by alkylation of ε-amino residue instead of the glycation with sugars, and was weakened by depletion of L or G.
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