2012 Fiscal Year Final Research Report
Development of Catalytic Construction of Carbon Frameworks Oriented to Conceptually Novel Medicinal Chemistry
| Project/Area Number |
23790007
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical pharmacy
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 有機化学 / 有機合成 / 医薬化学 / 触媒 / 酸素酸化 / アミノ酸 |
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| Research Abstract |
Three novel catalytic systems composed of first-row transition metal and organo-redox mediator have been developed. The catalytic systems can oxidize compound via [1e+1e] mechanism to produce attractive medicinal building blocks in short steps, such as non-natural ?-amino acid surrogate, C(2)-andC(3)-functionalized amines.
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[Presentation] Catalytic migratory oxidative coupling of nitrones2011
Author(s)
Kounosuke Oisaki, Shogo Hashizume, Motomu Kanai
Organizer
The 6th International Conference on Cutting-Edge Organic Chemistry in Asia / The 2nd New Phase International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-6/ NICCEOCA-2)
Place of Presentation
香港(中国)
Year and Date
20111211-1215
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