2012 Fiscal Year Final Research Report
Mechanisms underlying evolutionary architecture of primary sensory neurons in chordates
| Project/Area Number |
23790234
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
General anatomy (including Histology/Embryology)
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| Research Institution | Jichi Medical University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 発生 / 進化 / 分化 / 一次感覚神経 / 脊髄神経節 / 神経堤細胞 / エンハンサー / Six遺伝子 |
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| Research Abstract |
We found 1) Six1 is a key regulator of transition from intramedullary primary sensory neurons to extramedullary sensory neurons during Xenopus development, 2) early expression of Six1 prevents the appearance of intramedullary sensory neurons in mouse spin
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