2012 Fiscal Year Final Research Report
Metabolic regulations by adrenomedullin-RAMP2 system
| Project/Area Number |
23790288
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
General pharmacology
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| Research Institution | Shinshu University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 生理活性物質 / メタボリックシンドローム |
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| Research Abstract |
Adrenomedullin (AM) is a vasodilating peptide. Receptor activity-modifying protein 2 (RAMP2) is the critical determinant of vascular functions of AM. In high-fat diet fed RAMP2 heterozygous knockout mice and adipocyte-specific RAMP2 knockout mice analysis, these observations indicate that AM-RAMP2 system play critical roles in the regulation of glucose and lipid metabolism and adipocyte development.
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Research Products
(12 results)
