2012 Fiscal Year Final Research Report
Analysis of shiga-toxin resistance systemin enterohemorrhagic E. coli
| Project/Area Number |
23790478
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Bacteriology (including Mycology)
|
|---|
| Research Institution | University of Miyazaki |
|---|
Principal Investigator |
OGURA Yoshitoshi 宮崎大学, フロンティア科学実験総合センター, 助教 (40363585)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Keywords | 病原性 |
|---|
| Research Abstract |
Major virulence factor of enterohemorrhagic E. coliis shiga toxin (Stx) which inhibits protein synthesis of the host cell by depurinating a specific adenine residue of 28S rRNA. The E. coli K-12 also exhibits growth defect by introduction and expression of Stx. However O157 strain is resistant to Stx. In this study, from the analysis of O157 fosmid clones which confer Stx resistance to K-12, three genomic regions of O157 genome related to the Stx resistance were identified.
|
-
-
-
[Journal Article] Complete Genome Sequence of a Propionibacterium acnes Isolate from a Sarcoidosis Patient.2013
Author(s)
K.Minegishi, C. Aikawa, A. Furukawa, T. Watanabe, T. Nakano, Y. Ogura, Y. Ohtsubo, K. Kurokawa, T. Hayashi, F. Maruyama, I. Nakagawa, Y
-
Journal Title
Genome Announc.
Volume: 1(1)
Pages: e00016-12
DOI
-
-
-
-
[Journal Article] Hemolysin E- and enterohemolysin-derived hemolytic activity of O55/O157 strains and other Escherichia colilineages.2012
Author(s)
K. Murase, T. Ooka, A. Iguchi, Y. Ogura, K. Nakayama, Md. Asadulghani, Md. R. Islam, H. Hiyoshi, T. Kodama, L. Beutin, T. Hayashi
-
Journal Title
Microbiology
Volume: 158
Pages: 746-758
DOI
Peer Reviewed
-
[Journal Article] Clinical significance of Escherichia albertii2012
Author(s)
T. Ooka, K. Seto, K. Kawano, H. Kobayashi, Y. Etoh, S. Ichihara, A. Kaneko, J. Isobe, K. Yamaguchi, K. Horikawa, T.A.T. Gomes, A. Linden, M. Bardiau, J. Mainil, L. Beutin, Y. Ogura, T. Hayashi
-
Journal Title
Emerg. Infect. Dis
Volume: 18(3)
Pages: 488-492
Peer Reviewed
-
-
[Journal Article] Whole-genome sequence of a hypervirulent clinical Mycobacterium intracellularestrain2012
Author(s)
Y. Tateishi, S. Kitada, K. Miki, R. Maekura, Y. Ogura, Y. Ozeki, Y. Nishiuchi, M. Niki, T. Hayashi, K. Hirata, K. Kobayashi, S. Matsumoto
-
Journal Title
M.i.198. J. Bacteriol.
Volume: 194(22)
Pages: 6336
DOI
Peer Reviewed
-
-
-
-
-
[Journal Article] The lifestyle of the segmented filamentous bacterium: a nonculturable gut-associated immunostimulating microbe inferred by whole-genome sequencing2011
Author(s)
T. Kuwahara, ,Y. O g u r a, K. Oshima, K. Kurokawa, T, Ooka, H. Hirakawa, T, Itoh. H. Nakayama-Imaohji, M. Ichimura, K. Itoh, C. Ishifune, Y. Maekawa, K. Yasutomo, M. Hattori, T. Hayashi
-
Journal Title
DNA Res
Volume: 18
Pages: 291-303
DOI
Peer Reviewed
-
-
[Journal Article] IS621-based multiplex PCR printing method of O26 enterohaemorrhagic and enteropathogenic Escherichia coliisolated from humans and cattle2011
Author(s)
J.G. Mainil, M. Bardiau, T. Ooka, Y. Ogura, K. Murase, Y. Etoh, S. Ichihara, K. Horikawa, G. Buvens, D. Pierard, T. Itoh, T. Hayashi
-
Journal Title
J. Appl. Microbiol
Volume: 111
Pages: 773-786
DOI
Peer Reviewed
-
-
-
-
[Presentation] 腸管出血性大腸菌O26におけるゲノムアダプテーション解析2013
Author(s)
小椋義俊, 桂啓介, 伊藤武彦, Mainil Jacques , 吉野修司, 磯部順子, 勢戸和子, 江藤良樹, 黒木真理子, 木全恵子, 前田詠里子, 後藤恭宏, 大岡唯祐, 林哲也
Organizer
第7回日本ゲノム微生物学会年会
Place of Presentation
長浜
Year and Date
20130308-10
-
-
-
-
[Presentation] 腸管侵入性大腸菌のゲノム解析2012
Author(s)
小椋義俊,大岡唯祐,磯部順子,河野喜美子, 松本昌門, 勢戸和子, 岩出義人,緒方喜久代, 林哲也
Organizer
第6回日本ゲノム微生物学会年会
Place of Presentation
東京
Year and Date
20120310-12
-
-
-
-
-
