2013 Fiscal Year Final Research Report
Evaluation between gene-polymorphism and efficacy of therapy for pulmonary arterial hypertension using next-generation DNA analysis system
| Project/Area Number |
23791144
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Pediatrics
|
|---|
| Research Institution | Asahikawa Medical College |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Keywords | 肺高血圧症 / 先天性心疾患 |
|---|
| Research Abstract |
We studied pulmonary arterial hypertension in children with congenital heart disease. Serum high sensitivity cTnI levels significantly correlated with Pp/Ps in children. The Qs and Qp/Qs obtained by MRI strongly correlated with those obtained by catheterization, and a significant correlation was observed between the MCFR and Pp/Ps. Moreover, unlike patients with regressed CALs (coronary arterial lesion) in Kawasaki Disease, patients with persistent CALs have abnormal mechanical properties and hemodynamics of the pulmonary artery.
|
Research Products
(15 results)
