2013 Fiscal Year Final Research Report

The new criteria for transfusion to infant with anemia of prematurity based on the cerebral hemodynamics.

Research Project

Project/Area Number	23791228
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Embryonic/Neonatal medicine
Research Institution	Kagawa University
Principal Investigator	KOYANO Kosuke 香川大学, 医学部附属病院, 助教 (20437685)
Project Period (FY)	2011 – 2013
Keywords	未熟児貧血 / 近赤外光 / 脳血液量 / 脳内酸素飽和度 / 輸血
Research Abstract	This study shows that transfusion decreases cerebral blood volume and increases cerebral oxygen saturation in infants with anemia of prematurity. In particular, changes in cerebral blood volume are greater when the hemogrobin level is low before transfusion. The use of time-resolved spectroscopy provides a non-invasive approach. Our results suggest that the cerebral blood volume and cerebral oxygen saturation may be useful criteria for determining the need for transfusion in preterm infants.