2012 Fiscal Year Final Research Report
Development of an innovative system for cancer diagnosis and therapy; from diagnosis and therapy for bone metastases to DDS
| Project/Area Number |
23791401
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Kanazawa University |
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Principal Investigator |
OGAWA Kazuma 金沢大学, 薬学系, 准教授 (30347471)
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| Project Period (FY) |
2011 – 2012
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| Keywords | DDS / ナノパーティクル / セラノスティクス / PET |
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| Research Abstract |
Drug delivery system (DDS), which is for delivery of anticancer drugs to cancer tissue, is very important because it enhances the therapeutic effects and reduces the side effects. The aim of this study is development of a DDS using hydroxyapatite as a nanoparticle carrier. A novel cancer diagnosis and therapy DDS, which is a conjugation between a radiolabeled compound with high bone affinity and hydroxyapatite, was synthesized and evaluated.
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