2012 Fiscal Year Final Research Report
New application of diffusion weighted imaging: Quantification of perfusion
| Project/Area Number |
23791404
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | University of Yamanashi |
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Principal Investigator |
MOTOSUGI Utaroh 山梨大学, 医学工学総合研究部, 助教 (50377579)
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| Project Period (FY) |
2011 – 2012
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| Keywords | MRI / 拡散強調像 |
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| Research Abstract |
In this study, we studied new MR imaging technique using IVIM-DWI model to quantify not only diffusivity parameter of the proton but also perfusion parameter of the tissue. First, we evaluated the differences and variations of the ways of approximation to the model. As a result, we elucidated that the results of approximation using IVIM-DWI model can vary widely depending upon the way of approximation. In the preliminary study with clinical cases, we found that perfusion related parameter, D*, was well correlated with the renal function, which indicated the D* can reflect the renal perfusion. Conclusion: IVIM-DWI model can non-invasively estimate the perfusion related parameter.
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