Visualization of pelvic fibrosis on MR imaging

2013 Fiscal Year Final Research Report

• Project/Area Number: 23791410
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Kyoto University
• Principal Investigator: AKI Kido 京都大学, 医学(系)研究科(研究院), 助教 (80595710)
• Project Period (FY): 2011 – 2012
• Keywords: 子宮 / 磁化移動効果

Research Abstract

Off resonance saturation imaging is a magnetic resonance imaging (MRI) technique that selectively alters the contrast on the basis of tissue macromolecular environments by magnetization transfer and spin lock. The contrast obtained is highly dependent on the offset frequency.
After examination using phantom on 1.5T MR magnet, ECR image of brain showed clear difference between grey matter and white matter. As for the female pelvic region, intestinal movement made considerable artifact on ECR image and difficult to analyze. As a result, objective for ECR image was changed to uterine fibroids. In seven cases with uterine fibroids, ECR value tended to be higher than normal uterine myometrium. This result may reflect less free water due to packed smooth muscle cell, fibroblasts and collagen in fibroids than normal uterine myometrium. Comparison between ECR values and change of signal intensity on T2WI of uterine fibroids may lead to the degree of degeneration within leiomyma as a next step.

Research Products

• [Journal Article] Advanced MR imaging in Malignant Neoplasms of the Uterus (2013)
  • Author(s): Kido A, Fujimoto K, Okada T, Togashi K.
  • Journal Title: J Magn Reson Imaging Volume: 37(2) Pages: 249-64
• [Journal Article] Anticholinergic agents result in weaker and shorter suppression of uterine contractility compared with intestinal motion : time course observation with cine MRI (2013)
  • Author(s): Daido S, Nakai A, Kido A, Okada T, Kamae T, Fujimoto K, Ito I, Togashi K.
  • Journal Title: J Magn Reson Imaging
• [Journal Article] Changes of the normal ovary during menstrual cycle in reproductive age on the diffusion-weighted image (2012)
  • Author(s): Morisawa N, Kido A, Koyama T, Okada T, Kataoka M, Umeoka S, Fujimoto K, Tamai K, Togashi K.
  • Journal Title: J Comput Assist Tomogr Volume: 36(3) Pages: 319-22
• [Presentation] ASTER(ASL)法を用いた腎MRI perfusionにおける基礎的検討 (2012)
  • Author(s): 高倉京子、藤本晃司、木戸晶、佐川肇、梅岡成章、坂下尚孝、木村徳典、富樫かおり
  • Organizer: 第40回日本磁気共鳴医学会大会
  • Place of Presentation: 京都国際会館
  • Year and Date: 20120906-08
• [Presentation] Water fat opposed phase (WFOP) sequence is a robust fat suppression technique under the presence of B0 inhomogeneity in abdominal MRI at 3.0 T (2011)
  • Author(s): Kido, A. Fujimoto, K. Okada, T. Kusahara, H. Wheaton, A. Miyazaki, M, Togashi, K.
  • Organizer: ISMRM 19th Annual Meeting Montreal
  • Place of Presentation: Montréal, Québec, Canada
  • Year and Date: 20110506-13
• [Presentation] Uterine appearance and uterine peristalsis during lactaion on MR imaging (2011)
  • Author(s): Daido S, Nakai A., Kido A., Fujimoto K., Kusahara H., and Togashi K.
  • Organizer: The 19th Annual Scientific Meeting and Exhibition of The International Society for Magnetic Resonance in Medicine. Quebec
  • Place of Presentation: Canada
  • Year and Date: 20110500