2012 Fiscal Year Final Research Report

Optimization of synthesis methods and synthesis condition in C-11 labeling

Research Project

Project/Area Number	23791420
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Radiation science
Research Institution	Osaka University
Principal Investigator	KANAI Yasukazu 大阪大学, 大学院・医学系研究科, 寄附講座助教 (60397643)
Project Period (FY)	2011 – 2012
Keywords	PET / 標識合成 / Loop 法 / オンカラム法 / 比放射能
Research Abstract	In this study, I have investigated about synthesis methods of Carbon -11 labeled PET ligand. I have revealed feature of each synthesis method by confirmingradioactivity of final products, specific activity synthesis method and so on with compare gas phase reaction and liquid phase reaction, bubbling method and liquid phase reaction or bubbling method and on-column methods

(1 results)