2013 Fiscal Year Final Research Report
Basic research to embolization uterie artery using NBCA Lipiodol in perinatal bleeding
| Project/Area Number |
23791444
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Keio University |
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Principal Investigator |
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| Research Collaborator |
INOUE Masanori 慶應義塾大学, 医学部, 共同研究員 (30338157)
UENO Akihisa 慶應義塾大学, 医学研究科, 大学院生 (80348755)
NAKATSUKA Seishi 慶應義塾大学, 医学部, 講師 (50188984)
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| Project Period (FY) |
2011 – 2013
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| Keywords | NBCA / 偽妊娠豚子宮動脈塞栓 / 子宮動脈塞栓 |
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| Research Abstract |
Perinatal bleeding is a condition that threatens the life of patient.Now, embolization from the uterine artery has been attempted. And embolization using NBCA has also increased.But there were a few pathological basic research after using NBCA.
First, the uterine artery of two pigs was embolization using lipiodol and NBCA. Hysterectomy was performed to examine the extent of the NBCA and Lipiodol, and to observe in pathologic evaluation. The distribution of embolization material evaluated by soft X-ray was almost concordant by pathological evaluation. Second, after embolization using NBCA, two pigs were fed two weeks. Then angiography was performed to evaluate in the extent of embolic material. Then, we examined pathologically extent of embolic material, the effects on endometrium. In two weeks, it appeared that the degree of residual intravascular embolic material had different concentrations, but not change the extent of the range of distribution.
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