2013 Fiscal Year Final Research Report
Molecular genetic analyses of bone and soft tissue tumors
| Project/Area Number |
23791627
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
KIMURA Ayako 東京医科歯科大学, 硬組織疾患ゲノムセンター, 特任助教 (30597232)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 骨軟部腫瘍 |
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| Research Abstract |
Genetic analysis was performed using human osteosarcoma samples, failed to detect any apparent genetic alterations. Using osteosarcoma cell line, we isolated the genes involving the development and progression of osteosarcoma. Overexpression and knockdown of the gene demonstrated its function in cell proliferation, migration and invasion.
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