2012 Fiscal Year Final Research Report
Homing of circulating osteogenic progenitors to fracture healing site by administration of parathyroid hormone
| Project/Area Number |
23791652
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Yokohama City University |
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Principal Investigator |
KUMAGAI Ken 横浜市立大学, 医学部, 助教 (10468176)
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| Research Collaborator |
GEORGE F Muschler Cleveland Clinic, Orthopaedic Research Center, Director
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| Project Period (FY) |
2011 – 2012
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| Keywords | PTH / 骨折治癒 / 骨前駆細胞 / ホーミング |
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| Research Abstract |
This study demonstrated that bone formation was stimulated through the homing of circulating osteogenic cells by the intermittent administration of parathyroid hormone in mouse femur fracture model. The data also suggested that SDF-1/CXCR4 contributed to the homing of the circulating osteogenic cells.
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Research Products
(15 results)
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[Presentation] Effect of total knee arthroplasty with capsulosynovectomy on disease activity in rheumatoid arthritis patients treated with biological therapy2012
Author(s)
Kumagai K, Kusayama Y, Inaba Y, Matsuo K, Harigane K, Yukizawa Y, Kubota A, Muramatsu S, Nagaoka A, Fujisaki M, Saito T
Organizer
The 22nd Japanese-Korean Combined Orthopaedic Symposium
Place of Presentation
Nikko Senhime Monogatari Inn, Tochigi, Japan
Year and Date
20120607-09
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[Presentation] 中等度以上の疾患活動性を有する生物学的製剤投与関節リウマチ患者に対する滑膜切除を併用した人工膝関節置換術が疾患活動性に及ぼす影響2012
Author(s)
熊谷研, 稲葉裕, 松尾光祐,藤原豊,雪澤洋平,草山喜洋,鈴木宙,富岡政光,長岡亜紀子,藤崎真理,齋藤知行
Organizer
第56回日本リウマチ学会総会・学術集会
Place of Presentation
グランドプリンスホテル新高輪(東京都)
Year and Date
20120426-29
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