2012 Fiscal Year Final Research Report
Interaction between genetic polymorphisms in estrogen metabolism and environmental factors on Japanese endometrial cancer risk
| Project/Area Number |
23791866
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Aichi Cancer Center Research Institute |
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Principal Investigator |
HOSONO Satoyo 愛知県がんセンター(研究所), 疫学・予防部, 主任研究員 (80402600)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 遺伝子環境交互作用 / エストロゲン代謝関連遺伝子多型 / 子宮体癌 |
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| Research Abstract |
To assess the association between endometrial cancer and genetic polymorphisms in estrogen metabolism, we conducted a case-control study based on the Hospital-based Epidemiologic Research Program at Aichi Cancer Center (HERPACC study). We found no significant association between genetic polymorphisms in estrogen metabolism and endometrial cancer risk and no significant interaction between these polymorphisms and current BMI.
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