Regeneration of laryngeal cartilage using autologous chondrocytes

2013 Fiscal Year Final Research Report

• Project/Area Number: 23791918
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Otorhinolaryngology
• Research Institution: Fukushima Medical University
• Principal Investigator: NOMOTO Mika 福島県立医科大学, 医学部, 助教 (50554416)
• Project Period (FY): 2011 – 2013
• Keywords: 再生医療 / 喉頭軟骨 / 人工気管

Research Abstract

We developed a bio-engineered prosthesis with autologous chondrocytes and evaluate its effects on laryngeal regeneration by implantation into the tracheal defects of rabbits. As a result, regeneration of laryngeal cartilage. Regenerated cartilage can function as a frame for the trachea.

Research Products

• [Journal Article] Bioengineered trachea using autologous chondrocytes for regeneration of carteilage in a rabbit model (2013)
  • Author(s): Mika Nomoto, Yukio Nomoto, Yasuhiro Tada, et al
  • Journal Title: Laryngoscope Volume: 123(9) Pages: 2195-2201
• [Presentation] 自家軟骨細胞付加人工気管を用いた気管軟骨の再生 (2013)
  • Author(s): 野本美香
  • Organizer: 第12回日本再生医療学会
  • Place of Presentation: 横浜
  • Year and Date: 2013-03-23
• [Presentation] Tracheal cartilage regeneration using autologous chondrocytes (2012)
  • Author(s): Nomoto Mika
  • Organizer: The 8th East Asian Conference on Phonosurgery
  • Place of Presentation: 韓国
  • Year and Date: 2012-12-01
• [Presentation] 自家軟骨細胞を導入した新規人工気管の開発 (2012)
  • Author(s): 野本美香
  • Organizer: 第113回日本耳鼻咽喉科学会総会
  • Place of Presentation: 新潟
  • Year and Date: 2012-05-12
• [Presentation] Bio-Engineered Trachea using Autologous Chondrocytes for Regeneration of Tracheal Cartilage in a Rabbit Model (2012)
  • Author(s): Nomoto Mika
  • Organizer: American Laryngological Assosiation
  • Place of Presentation: アメリカサンディエゴ
  • Year and Date: 2012-04-19
• [Presentation] Regeneration of tracheal cartilage using autologous chondrocytes in a rabbit model (2011)
  • Author(s): Nomoto Mika
  • Organizer: 11th Japan-Taiwan Conference on Otolaryngology-Head and Neck Surgery
  • Place of Presentation: 神戸市
  • Year and Date: 2011-12-08
• [Presentation] 自家軟骨細胞を用いた気管再生の試み (2011)
  • Author(s): 野本美香
  • Organizer: 第112回日本耳鼻咽喉科学会
  • Place of Presentation: 京都府
  • Year and Date: 2011-05-20
• [Presentation] Regeneration of tracheal cartilage by bio-engineered trachea with autologous chondrocytes (2011)
  • Author(s): Nomoto Mika
  • Organizer: American Broncho-Esophagological Association
  • Place of Presentation: アメリカイリノイ州シカゴ
  • Year and Date: 2011-04-28