2012 Fiscal Year Final Research Report
Genome sequencing and mutational analysis of the Actinomyces strains with enhanced biofilm phenotype
| Project/Area Number |
23792118
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Morphological basic dentistry
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| Research Institution | Osaka Dental University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 口腔細菌学 / バイオフィルム |
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| Research Abstract |
To find out the mechanism of biofilm formation of oral Actinomyces, genome and genetic analysis were carried out for two strains of K20 and MG-1 keeping enhanced biofilm phenotype. The genome of the strain K20 was almost completely sequenced and the given data was uploaded to the public database（DDBJ, BABV01000001-BABV01000771）. Additionally, I have identified some biofilm-related genes by mutation analysis and have reported this.
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[Journal Article] Biofilm-forming capacity on clinically isolated Streptococcus constellatus from an odontogenic subperiosteal abscess lesion2013
Author(s)
Yamanaka T, Furukawa T, Yamane K, Nambu T, Mashimo C, Maruyama H, Inoue J, Kamei M, Yasuoka H, Horiike S, Leung KP, Fukushima H
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Journal Title
Bacteriology & Parasitology
Volume: 4
Pages: 1000160
DOI
Peer Reviewed
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[Journal Article] Identification of thegenes involved in the biofilm-likestructures onActinomyces oris K20, aclinical isolate from an apical lesion2013
Author(s)
Mashimo C, Kamitani H, Nambu T, YamaneK, Yamanaka T, Sugimori-Shinozuka C,Tatami T, Inoue J, Kamei M, Morita S, Leung KP, Fukushima H
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Journal Title
Journal of Endodontics
Volume: 39
Pages: 44-48
DOI
Peer Reviewed
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