2012 Fiscal Year Final Research Report
The age-related changes in taste transduction and perception mechanisms
| Project/Area Number |
23792136
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Functional basic dentistry
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| Research Institution | Osaka Dental University |
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Principal Investigator |
INUI Chizuko (YAMAMOTO Chizuko) 大阪歯科大学, 歯学部, 助教 (00419459)
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| Research Collaborator |
YAMAMOTO Takashi 畿央大学, 健康科学部, 教授 (60028793)
UEDA Katsura 大阪歯科大学, 歯学部, 講師 (50448106)
NAKATSUKA Michiko 大阪歯科大学, 歯学部, 講師 (70368158)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 加齢 / 味覚嗜好性 / 味細胞 / 味神経 / 鼓索神経 / 脳機能 |
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| Research Abstract |
It remains unclear how aging affect food preferences. Thus, we investigated the age-related changes in taste palatability, and neural mechanisms of those changes. Behavioral studies using rats revealed that taste sensitivity was higher in older age than younger rats. We also found that aging cause shift in palatability of sweet, umami and bitter taste solutions. These behavioral changes were not due to alteration in morphology of taste cells and the electrophysiological responses of taste nerve. Therefore, it is suggested that age-related changes in taste sensitivity and palatability are accounted for by development of central nervous system rather than peripheral.
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Research Products
(14 results)
