2013 Fiscal Year Final Research Report
Effect of peptide relating to food intake behavior on swallowing in the developmental process
| Project/Area Number |
23792424
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Niigata University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
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| Keywords | 嚥下 / 摂食 / ペプチド |
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| Research Abstract |
One of the factors to feel satiety is an increase in blood glucose. Increase in blood insulin level caused by an increase in blood glucose regulate feeding behavior. On the other hand, sweet taste stimulation induce transient insulin secretion before increase in blood glucose level(Cephalic Phase of Insulin Release;CPIR).
In the present study, I investigated the effect of taste stimulation in the pharynx. Out of taste stimulants tested, acid solution facilitated initiation of swallow, in that the swallowing interval was significantly shorter during acid stimulation as compared to other taste ones. Sensory scale of taste intensity during swallowing was higher in acid solution. The results suggest that the effect of taste stimulation varies among tastants, and that acid stimulation may facilitate swallowing.
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