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2012 Fiscal Year Final Research Report

The function of anti-cardiolipin antibody by periodontal pathogen for neovascular glaucoma

Research Project

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Project/Area Number 23792466
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Periodontal dentistry
Research InstitutionTokyo Medical and Dental University

Principal Investigator

KATAGIRI Sayaka  東京医科歯科大学, 大学院・医歯学総合研究科, 助教 (60510352)

Project Period (FY) 2011 – 2012
Keywords歯周病 / 血管新生緑内障 / 自己抗体 / anti-cardiolipin 抗体 / 交差反応
Research Abstract

We showed the possibility of cross reaction between the anti-SIRVYK antibody (SIRVYK is peptide sequence of leucotoxin C in A. actinomycetencomitans) and TLRVYK peptide on beta 2 GPI. We find the correlation between serum anti-SIRVYK antibody and serum anti-TLRVYK antibody in diabetic patients. These results might suggest that there is a possibility about relationship between periodontal diseases and neovascular glaucoma.

  • Research Products

    (17 results)

All 2013 2012 2011 Other

All Journal Article (7 results) Presentation (8 results) Book (2 results)

  • [Journal Article] Effect of glycemic control on periodontitis in type 2 diabetic patients with periodontal disease2013

    • Author(s)
      Katagiri S, Nitta H, Nagasawa T, Izumi Y, Kanazawa M, Matsuo A, Chiba H, Fukui M, Nakamura N, Oseko F, Kanamura N, Inagaki K, Noguchi T, Naruse K, Matsubara T, Miyazaki S, Miyauchi T, Ando Y, Hanada N, Inoue S
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 4(3) Pages: 320-325

  • [Journal Article] Histological and SEM analysis of root cementum following irradiation with Er:YAG and CO2 lasers2013

    • Author(s)
      Almehdi A, Aoki A, Ichinose S, Taniguchi Y, Sasaki KM, Ejiri K, Sawabe M, Chui C, Katagiri S, Izumi Y
    • Journal Title

      Lasers in Medical Science

      Volume: 28(1) Pages: 203-213

  • [Journal Article] Periodontal treatment with topical antibiotics improves glycemic control in association with elevated serum adiponectin in patients with type 2 diabetes mellitus2013

    • Author(s)
      Bhartia P, Katagiri S, Nitta H, Nagasawa T, Kobayashi H, Takeuchi Y, Izumiyama H, Uchimura I, Inoue S, Izumi Y
    • Journal Title

      Obesity Research and Clinical Practice

      Volume: 7(2) Pages: e129-138

  • [Journal Article] Salivary levels of antibacterial peptide (LL-37/hCAP-18) and cotinine in periodontitis patients2012

    • Author(s)
      Takeuchi Y, Nagasawa T, Katagiri S, Kitagawara S, Kobayashi H, Koyanagi T, Izumi Y
    • Journal Title

      Journal of Periodontology

      Volume: 83(6) Pages: 766-772

  • [Journal Article] Improvement of glycemic control after periodontal treatment by resolvinggingival inflammation in type 2 diabetic patients with periodontal disease2012

    • Author(s)
      Katagiri S, Nagasawa T, Kobayashi H, Takamatsu T, Bharti P, Izumiyama H, Uchimura I, Tagami T, Suzuki T, Nanbara H, Taniguchi Y, Hayakumo S, Koyanagi T, Himeno-Ando A, Goto M, Kajio H, Takahashi Y, Izumi Y, Noda M
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 3(4) Pages: 402-409

  • [Journal Article] Reduced masticatory function innon-elderly obese Japanese adults2011

    • Author(s)
      Katagiri S, Nitta H, Nagasawa T, Izumi Y, Kanazawa M, Matsuo A, Chiba H, Miyazaki S, Miyauchi T, Nakamura N, Oseko F, Kanamura N, Ando Y, Hanada N, Inoue S
    • Journal Title

      Obesity Research and Clinical Practice

      Volume: 5(4) Pages: e279-286

  • [Journal Article] The anti-phospholipid antibody-dependent and independent effects ofperiodontopathic bacteria on threatened preterm labor and preterm birth

    • Author(s)
      Ye C, Katagiri S, Miyasaka N, Bharti P, Kobayashi H, Takeuchi Y, Momohara Y, Sekiguchi M, Takamine S, Nagasawa T, Izumi Y
    • Journal Title

      Archives of Gynecology and Obstetrics

      Volume: (in press)

  • [Presentation] Periopathogenic Bacteria in Oral Plaque2013

    • Author(s)
      Ye C, Bharti P, Kobayashi H, Katagiri S, Takeuchi Y, Nagasawa T, Izumi Y
    • Organizer
      Saliva and Placenta from PLBW91st General Session & Exhibition of theIADR
    • Place of Presentation
      Seattle, USA
    • Year and Date
      20130320-23
  • [Presentation] 歯周炎に罹患した2型糖尿病患者における歯周病治療および糖尿病治療による多施設介入研究2012

    • Author(s)
      片桐さやか,新田浩,長澤敏行,泉山肇,内村功,野口俊英,菊池毅,稲垣幸司,松原達昭,成瀬桂子,金澤真雄,松尾朗,千葉博茂,大迫文重,金村成智,福井道明,中村直登,井上修二,和泉雄一
    • Organizer
      第22回日本歯科医学会総会
    • Place of Presentation
      大阪
    • Year and Date
      20121109-11
  • [Presentation] 糖尿病・肥満患者における口腔に関する多施設疫学研究2012

    • Author(s)
      新田浩,片桐さやか,長澤敏行,和泉雄一,金澤真雄,松尾朗,千葉博茂,宮崎滋,宮内孝,大迫文重,金村成智,福井道明,中村直登,安藤雄一,花田信弘,井上修二.
    • Organizer
      第22回日本歯科医学会総会
    • Place of Presentation
      大阪
    • Year and Date
      20121109-11
  • [Presentation] The role of antibodies against periodontal pathogen on preterm birth2012

    • Author(s)
      Ye C, Katagiri S, Bharti P, Kobayashi H, Takeuchi Y, Nagasawa T, Izumi Y
    • Organizer
      The 98th Annual Meeting of the American Academy of Periodontology
    • Place of Presentation
      Los Angeles, USA
    • Year and Date
      20120929-1002
  • [Presentation] Expression of CD14, CD16 and CD45 on monocytes from aggressive periodontitis patients2012

    • Author(s)
      Bharti P, Katagiri1 S, Ye C, Kobayashi H, Takeuchi Y, Nagasawa T, Izumi Y
    • Organizer
      EuroPerio7
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      20120606-09
  • [Presentation] Salivary levels of antibacterial peptide (LL-37/hCAP-18) and cotinine in periodontitis patients2012

    • Author(s)
      Takeuchi Y, Nagasawa T, Katagiri S, Kitagawara S, Kobayashi H, Koyanagi T, Izumi Y
    • Organizer
      EuroPerio7
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      20120606-09
  • [Presentation] 早産・低体重児出産における歯周病に起因したβ2glycoprotein-Iを認識する抗体の役割2012

    • Author(s)
      葉暢暢,片桐さやか,バルティパリクシャ,小林宏明,竹内康雄,長澤敏行,和泉雄一
    • Organizer
      第55回春季日本歯周病学会学術大会
    • Place of Presentation
      札幌
    • Year and Date
      20120517-19
  • [Presentation] The role of periodontal bacteria on antiphhospholipid syndrome and preterm low birth weight2012

    • Author(s)
      Ye C, Katagiri S, Bharti P, Kobayashi H, Takeuchi Y, Nagasawa T, Izumi Y
    • Organizer
      Japan-China Dental Conference 2012
    • Place of Presentation
      Sichuan, China
    • Year and Date
      2012-04-27
  • [Book] プラクティス2011

    • Author(s)
      片桐さやか,和泉雄一
    • Total Pages
      239-241
  • [Book] The Bone2011

    • Author(s)
      和泉雄一、片桐さやか
    • Total Pages
      421-425

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Published: 2014-09-25  

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