2012 Fiscal Year Final Research Report
High throughput single molecule manipulation device for real-time observation of DNA binding proteins
| Project/Area Number |
23810034
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | Nagoya University |
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Principal Investigator |
ARATA Hideyuki 名古屋大学, 理学研究科, 特任講師 (00582446)
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| Project Period (FY) |
2011 – 2012
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| Keywords | MEMS / DNA / 一分子計測 / ハイスループット |
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| Research Abstract |
Future goal of this project was to develop high-throughput single molecule system utilizing technical aspects of both bioMEMS and single molecule manipulation. To achieve this goal, we have developed a silicon-based microdevice consists of two microchannels and multiple nanochannels. We also confirmed that a single DNA molecule can be inserted and manipulated in a nanochannel.
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