2015 Fiscal Year Final Research Report
Interdisciplinary research to accelerate making the Japanese fire-bellied newt a model animal: groundwork for technology and information and its practical application.
| Project/Area Number |
24240062
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Laboratory animal science
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
OBATA Shuichi 北里大学, 医療衛生学部, 准教授 (10204273)
NAKATANI Kei 筑波大学, 生命環境系, 教授 (20125040)
TAKESHIMA Kazuhito 名古屋大学, アイソトープ総合センター, 准教授 (20126874)
KINOSHITA Tsutomu 立教大学, 理学部, 教授 (30161532)
MARUO Fumiaki 筑波大学, 生命環境系, 助教 (30199921)
WATANABE Akihiko 山形大学, 理学部, 教授 (30250913)
ARIIZUMI Takashi 玉川大学, 農学部, 教授 (30286166)
ETO Ko 熊本大学, 大学院自然科学研究科, 准教授 (40359964)
TOYAMA Fubito 宇都宮大学, 工学研究科, 准教授 (60323317)
YAHATA Kensuke 筑波大学, 生命環境系, 講師 (70302370)
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| Project Period (FY) |
2012-05-31 – 2016-03-31
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| Keywords | 動物 / 生理学 / 発生・分化 / 環境 / ゲノム |
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| Outline of Final Research Achievements |
To install the resource, technology and information for the study of Japanese fire-bellied newt into various research areas, 1) we generated various lines of newts that were created by transgenesis or genome editing on demand, and established systems for cell tracking and conditional gene regulation by means of grafting of tissues from transgenic newts or by using cell-specific promoters. We successfully applied these systems to various research areas including the regenerative physiology. 2) We constructed a transcriptome database ‘IMORI’and opened it to the public (http://antler.is.utsunomiya-u.ac.jp/imori/). On the basis of sequence information in the database, molecular cloning and gene expression analyses were facilitated in various research areas. 3) We made it possible that the newt is reared from egg to juvenile (after metamorphosis) efficiently in Imori-no-Sato, the newt stock center in the field. We started to supply larvae and juveniles for research purpose.
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| Free Research Field |
再生生理学
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