Use of maternal blood and the umbilical cord for the assessment of fetal exposure to multiple chemicals: implications for future generations

2014 Fiscal Year Final Research Report

• Project/Area Number: 24310021
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Environmental impact assessment/Environmental policy
• Research Institution: Chiba University
• Principal Investigator: MORI Chisato 千葉大学, 医学(系)研究科(研究院), 教授 (90174375)
• Co-Investigator(Kenkyū-buntansha): KOMIYAMA Masatoshi 千葉大学, 大学院看護学研究科, 教授 (70175339) ; TODAKA Emiko 千葉大学, 予防医学センター, 教授 (30334212) ; HANAZATO Masamichi 千葉大学, 予防医学センター, 准教授 (00608656) ; MATSUNO Yoshiharu 千葉大学, 予防医学センター, 准教授 (00376378) ; NAKAOKA Hiroko 千葉大学, 予防医学センター, 助教 (60588648)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 環境影響評価 / 科学物質 / 次世代影響 / 複合曝露

Outline of Final Research Achievements

In this study, we aimed to assess the levels of polychlorinated biphenyl (PCB) in the maternal blood (serum PCB) to ascertain fetal exposure to multiple chemicals. We studied 419 mothers in early pregnancy, with mean age being 30.36 ± 5.30 years. The mean level of PCB in maternal blood was 0.26 ± 0.13 ng/g-wet. The PCB levels correlated with increasing age of the mother. However, we were unable to clearly differentiate the PCB levels between nulliparous and multiparas.

Free Research Field

環境医学