2015 Fiscal Year Final Research Report
The development of novel functional Py-Im polyamide conjugates for sequence-specific gene regulation
| Project/Area Number |
24310155
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Living organism molecular science
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| Research Institution | Kyoto University |
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Principal Investigator |
Bando Toshikazu 京都大学, 理学(系)研究科(研究院), 准教授 (20345284)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Keywords | Py-Im ポリアミド / 特定遺伝子制御 / DNA塩基配列認識 |
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| Outline of Final Research Achievements |
In our research, we developed novel functional Py-Im polyamide conjugates based on molecular design of DNA alkylating Py-Im polyamide conjugates.
In fact, we added various biological function to Py-Im polyamide conjugates in cell application by the chemical modification for the specific regulation of gene expression. And, we reported the results of our research.
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| Free Research Field |
ケミカルバイオロジー
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